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May 19, 2006

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Sugar cane cholesterol treatment doesn't work, German study says

By Lindsey Tanner, May 17, 2006.

CHICAGO (AP) - German research casts doubt on the effectiveness of a sugar cane-based ingredient sold as a cholesterol treatment in One-A-Day vitamins and other products marketed in dozens of countries.

The substance, called policosanol, worked no better than dummy pills in German adults with high levels of LDL cholesterol, the bad kind that can clog arteries and lead to heart problems.

Even in high doses, policosanol derived from Cuban sugar cane produced no meaningful changes in cholesterol levels during 12 weeks of treatment, said lead author Dr. Heiner Berthold of the German Medical Association's drug commission.

Most previous studies that reached the opposite conclusion were sponsored by a company founded by Cuba's National Center for Scientific Research to market policosanol, the German researchers said. The Cuban scientific centre didn't respond to requests for comment.

The German study involving 143 people appears in Wednesday's Journal of the American Medical Association.

Patients were randomly assigned to get policosanol in various doses or dummy pills for 12 weeks. There was no difference in the levels of LDL in volunteers in either group.

Berthold, executive secretary of the German Medical Association's drug commission, said his research doesn't rule out that policosanol might be effective in different ethnic groups or that other formulations might have different effects.

But he believes the product's claims have been overstated because there's no "mechanism of action" to explain how it might lower cholesterol.

Policosanol is a combination of alcohols that come from plant wax. Cuban sugar cane-based policosanol is sold in more than 40 countries, mostly as a cholesterol treatment, the researchers said. Other sources for the ingredient include wheat germ, rice, bran and beeswax. Policosanol products are widely available on the Internet and in stores.

Bayer Consumer Care uses sugar cane-based policosanol in its One-A-Day Cholesterol Plus vitamins and calls it "the leading complete multivitamin specially formulated with heart-supporting nutrients."

Bayer spokeswoman Tricia McKernan said the study "was not designed to address a claim that along with diet and exercise, policosanol can help maintain healthy cholesterol levels already within the normal range."

"Bayer makes only the latter claim, and agrees with the authors that consumers should always discuss their cardiovascular risk profile with their doctor," McKernan said.

Policosanol is marketed in Cuba as a natural medicine called PPG with purported benefits including lowering cholesterol levels, boosting energy and weight loss.

Juventud Rebelde, the Communist Youth newspaper, reported last year that about 250,000 people in Cuba take PPG and that it is exported to various other countries.

Andrew Shao, vice-president of scientific and regulatory affairs at the Council for Responsible Nutrition, a trade group for dietary supplement makers, said the new research "is only one study" and not the final word on policosanol.

Associated Press writer Anita Snow in Havana contributed to this report.

Castro says he will resign if US can prove he's wealthy

HAVANA, 16 (AFP) - Cuban President Fidel Castro said he would offer his resignation if his arch-rival, the United States, can prove that he has a huge personal fortune as claimed by Forbes magazine.

"If they prove that I have an account abroad, I will resign from my position, from my current responsibilities," Castro, who has ruled Cuba for 47 years, said in a lengthy television and radio appearance.

Earlier this month, Castro was listed by Forbes as the seventh wealthiest ruler with 900 million dollars.

The American magazine cited former Cuban officials as saying that Castro had skimmed profits from a Havana convention center, retail conglomerate Cimex and vaccine and pharmaceutical products firm Medicuba to amass his fortune.

Forbes noted, however, that "Castro, for the record, disagrees, insisting his personal net worth is zero."

China, Canada seek crude off Cuba, but not US

By Carlos Batista. AFP Friday May 12, 2006.

HAVANA (AFP) - China will send 12 hi-tech rigs to drill for oil in Cuban waters of the Gulf of Mexico, officials have confirmed, irking US lawmakers that US firms cannot prospect in nearby US waters.

Cuba has stepped up work on a total of 36 new oil wells with Chinese companies and Canada's Sherritt, about four kilometers (2.5 miles) off the north coast, officials said privately.

The communist Cuban government is generally tight-lipped about oil matters but this week has been more public.

The party newspaper, Granma, gave uncharacteristic front page play to news of the well, drilled to a record depth for Cuba, near Varadero east of Havana.

And diplomatic sources on Thursday said that India's ONGC Videsh and Norway's Norsk Hydro would join forces with Spain's Repsol to seek crude in the Gulf of Mexico.

That news came as US lawmakers, with oil prices soaring, grumbled ever more loudly about rivals prospecting in Cuban waters while US environmental laws make it all but impossible for US firms to do so in nearby US waters, even as the US embargo locks them out of Cuba.

In Washington Thursday, two Republican US lawmakers submitted a bill that would in effect ease the US economic embargo by allowing US firms to operate in Cuban waters.

"The American public would be shocked and stunned that as this country faces a serious energy crisis at home, countries like China, India, Canada, Spain and Norway are exploring and drilling 50 miles off the US coast," said Republican US Senator Larry Craig of Idaho.

US companies would be allowed to engage in any transaction necessary and could travel for business purposes without a special license from the US government, said Craig, joined by congressman Jeff Flake of Arizona.

"China, as our National Security Strategy points out, is trying to lock up resources around the world, and they are locking up resources in our own backyard where we can't even compete and play ball," argued Craig.

US media have reported that China was involved in the prospecting but Cuba has not announced a Chinese deal as such.

The deal with ONGC Videsh and Norsk Hydro, to be signed officially in Havana May 23, technically is not a new contract.

"Those companies are joining the existing one with Repsol to share risks," a European diplomat told AFP privately.

Repsol has rights to six of the 59 prospecting areas the Cuban government has been auctioning off since 1999. It carried out its first drilling in 2004 and while oil was found, Repsol said the crude was not of commercial grade.

Since then Repsol has been looking for partners to share the investment burden, and ONGC Videsh and Norsk Hydro each will be picking up 30 percent of the expenses, other sources said.

The gulf's waters were divided into economic exclusion zones of the United States, Mexico and Cuba under a deal that is still in effect signed during the government of then-US president Jimmy Carter.

Among other companies with prospecting rights if not projects there are Canada's Sherritt International and Brazil's state oil giant Petrobras.

Cuba has invited US firms to take part but the US economic embargo bars them from doing so.

Cuba produces about a third of the oil it consumes, with the rest imported under favorable terms from a key ally Venezuela.

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